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Warren Fiskus Selected Research

Neoplasms (Cancer)

1/2022Efficacy of CDK9 inhibition in therapy of post-myeloproliferative neoplasm (MPN) secondary (s) AML cells.
1/2021Superior efficacy of co-targeting GFI1/KDM1A and BRD4 against AML and post-MPN secondary AML cells.
1/2021EVI1 dysregulation: impact on biology and therapy of myeloid malignancies.
1/2020Mechanistic basis and efficacy of targeting the β-catenin-TCF7L2-JMJD6-c-Myc axis to overcome resistance to BET inhibitors.
9/2019Correction: Androgen Receptor Is the Key Transcriptional Mediator of the Tumor Suppressor SPOP in Prostate Cancer.
1/2019A phase II study of omacetaxine mepesuccinate for patients with higher-risk myelodysplastic syndrome and chronic myelomonocytic leukemia after failure of hypomethylating agents.
1/2019Targeting nuclear β-catenin as therapy for post-myeloproliferative neoplasm secondary AML.
1/2019Targetable genetic alterations of TCF4 (E2-2) drive immunoglobulin expression in diffuse large B cell lymphoma.
9/2017Targeting Histone Acetylation: Readers and Writers in Leukemia and Cancer.
1/2017BET protein bromodomain inhibitor-based combinations are highly active against post-myeloproliferative neoplasm secondary AML cells.
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Warren Fiskus Research Topics

Disease

31Neoplasms (Cancer)
01/2022 - 08/2007
16Leukemia
09/2017 - 05/2004
15Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2020 - 05/2004
9Breast Neoplasms (Breast Cancer)
01/2016 - 09/2005
5Prostatic Neoplasms (Prostate Cancer)
11/2021 - 10/2014
5Mantle-Cell Lymphoma (Lymphoma, Mantle Cell)
01/2020 - 07/2009
5BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
10/2008 - 02/2005
4Primary Myelofibrosis (Myelosclerosis)
01/2017 - 10/2012
3Neoplasm Metastasis (Metastasis)
11/2021 - 06/2008
3B-Cell Lymphoma (Lymphoma, B Cell)
09/2015 - 10/2012
3Triple Negative Breast Neoplasms
07/2014 - 04/2012
2Lymphoma (Lymphomas)
01/2021 - 07/2009
2Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse)
01/2021 - 01/2019
2Adenocarcinoma
10/2014 - 11/2012
1Disease Progression
01/2021
1Chronic Myelomonocytic Leukemia (Leukemia, Chronic Myelomonocytic)
01/2019
1Myelodysplastic Syndromes (Myelodysplastic Syndrome)
01/2019
1Thyroid Neoplasms (Thyroid Cancer)
01/2016
1Hairy Cell Leukemia
01/2016
1Melanoma (Melanoma, Malignant)
01/2016
1Uveal melanoma
08/2015
1Rheumatoid Arthritis
05/2014
1B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
05/2014
1Pulmonary Edema
12/2013

Drug/Important Bio-Agent (IBA)

21Proteins (Proteins, Gene)FDA Link
01/2020 - 08/2004
19Histone Deacetylase InhibitorsIBA
07/2014 - 08/2004
14PanobinostatIBA
01/2020 - 02/2005
9VorinostatFDA Link
07/2014 - 09/2005
8Heat-Shock Proteins (Heat-Shock Protein)IBA
12/2011 - 05/2004
7Histones (Histone)IBA
09/2017 - 02/2005
6Phosphotransferases (Kinase)IBA
01/2017 - 05/2004
4Histone Deacetylases (Histone Deacetylase)IBA
05/2014 - 10/2008
3ChromatinIBA
11/2021 - 01/2020
3Pharmaceutical PreparationsIBA
01/2021 - 10/2008
3Androgen Receptors (Androgen Receptor)IBA
09/2019 - 10/2014
3DNA (Deoxyribonucleic Acid)IBA
01/2019 - 10/2008
3midostaurinIBA
12/2013 - 05/2004
3Tyrosine Kinase InhibitorsIBA
12/2011 - 07/2006
3Small Interfering RNA (siRNA)IBA
07/2011 - 07/2005
3tanespimycin (17AAG)IBA
10/2008 - 02/2005
3LAQ824IBA
10/2008 - 08/2004
3Hydroxamic Acids (Hydroxamic Acid)IBA
10/2008 - 02/2005
2Transcription Factors (Transcription Factor)IBA
01/2021 - 08/2015
2CateninsIBA
01/2020 - 01/2019
2Bortezomib (Velcade)FDA Link
01/2020 - 10/2010
2CCAAT-Enhancer-Binding ProteinsIBA
01/2020 - 10/2010
2Janus KinasesIBA
01/2017 - 10/2012
2ruxolitinibIBA
01/2017 - 10/2012
2AntioxidantsIBA
01/2016 - 10/2010
2Bcl-2-Like Protein 11IBA
01/2016 - 09/2015
2MicroRNAs (MicroRNA)IBA
08/2015 - 10/2012
2TubulinIBA
07/2014 - 07/2005
2Trastuzumab (Herceptin)FDA Link
07/2014 - 09/2005
2Oncogene Proteins (Oncogene Protein)IBA
05/2014 - 06/2008
2DecitabineFDA Link
12/2013 - 05/2009
2dactolisibIBA
05/2013 - 11/2012
23-deazaneplanocinIBA
11/2012 - 09/2009
2tozasertibIBA
09/2012 - 10/2008
2Aurora KinasesIBA
09/2012 - 10/2008
2Estrogens (Estrogen)FDA Link
04/2012 - 08/2007
2Dasatinib (BMS 354825)FDA Link
05/2009 - 10/2006
2Molecular Chaperones (Chaperone, Molecular)IBA
06/2008 - 08/2004
2Imatinib Mesylate (Gleevec)FDA Link
10/2006 - 02/2005
1DilazepIBA
11/2021
1venetoclaxIBA
01/2021
1snake venom protein C activatorIBA
01/2021
1Immunoglobulins (Immunoglobulin)IBA
01/2019
1Immunoglobulin M (IgM)IBA
01/2019
1HomoharringtonineIBA
01/2019
1Arsenic Trioxide (Trisenox)FDA Link
01/2016
1VemurafenibIBA
01/2016
1Peroxidase (Myeloperoxidase)IBA
01/2016
1Oxidants (Oxidizing Agents)IBA
01/2016
1Proto-Oncogene Proteins B-rafIBA
01/2016
1PeroxiredoxinsIBA
01/2016
1Sirtuin 2IBA
01/2016
1ibrutinibIBA
09/2015
1Steroid Receptors (Steroid Receptor)IBA
08/2015
1abirateroneIBA
12/2014
1enzalutamideIBA
12/2014
1Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA
10/2014
1Cisplatin (Platino)FDA LinkGeneric
07/2014
1Poly(ADP-ribose) Polymerase InhibitorsIBA
07/2014
1veliparibIBA
07/2014
1pegfilgrastim (Neulasta)FDA Link
07/2014
1Cyclophosphamide (Cytoxan)FDA LinkGeneric
07/2014
1Taxoids (Taxanes)IBA
07/2014
1Doxorubicin (Adriamycin)FDA LinkGeneric
07/2014
1Paclitaxel (Taxol)FDA LinkGeneric
07/2014
1Auranofin (Ridaura)FDA Link
05/2014
1Janus Kinase InhibitorsIBA
05/2013
1MTOR InhibitorsIBA
05/2013
1Phosphatidylinositols (Phosphatidylinositol)IBA
04/2013
1moesinIBA
04/2013
1N-acetyltalosaminuronic acid (NAT)IBA
04/2013

Therapy/Procedure

11Therapeutics
01/2022 - 10/2010
2Castration
11/2021 - 12/2014
2Aftercare (After-Treatment)
12/2014 - 06/2008
1Induction Chemotherapy
01/2017
1Artificial Respiration (Mechanical Ventilation)
12/2013